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Chemistry majors have the opportunity to build collaborative research partnerships directly with Meredith faculty and participate in projects in the renowned Research Triangle Park, a hub of research and scientific achievement. Chemistry students may also receive financial awards to present the results of their research projects at local and national conferences.

Research

  • A chemistry student worked as part of a team to study DNA Extraction and Regeneration of Tylosema exculentum and Tylosema fassoglensis.
  • A team of chemistry students investigated an efficient synthetic route of Isoptilocaulin which has been shown to have medicinal properties making it a formidable antibiotic against both gram negative and gram positive bacteria. It has also been shown to be an effective chemotherapeutic agent against leukemia cells in vitro.
  • A student explored a novel chelation method for removing metal contaminants like arsenic and lead from water supplies.

 

Presentations

Research Presentations at Professional Meetings of the American Chemical Society (ACS)

  • Six undergraduate research students (Zeenat Razvi, Julia Bair, Nooria Razai, Sally Yacout, Meredith Hyatt, and Brittney Mitchell) attended and presented April 8-12, 2013 at the 245th National American Chemical Society Meeting in New Orleans, LA.  The following list includes all citations from Meredith (Meredith students/faculty are bold):
  • “Science of art:  From creation to authentication to preservation” Dr. Kassy A. Mies and Sayyeda Zeenat Razvi
  • “Reductive mechanism of iron release from the iron-siderophore, ferrioxamine B, by NaDH in the presence of the iron(II) chelator, TPEN,” Dr. Kassy A. Mies and Sayyeda Zeenat Razvi
  • “Investigation of the roles of several iron(II) chelators in the release of iron from ferrioxamine B via reduction by NADH,” Julia Bair and Dr. Kassy A. Mies
  • “FbpA:  A continuum between bacterial transferring and periplasmic binding protein,” Dr. Claire J Parker Siburt, Dr. Sambuddha Banerjee, D. Aruna Weerasinghe, Dr. Timothy A. Mietzner, and Dr. Alvin L. Crumbliss
  • “Efficient synthetic route to isopitlocaulin utilizing an intramolecular Diels-Alder reaction,” Dr. William A. Dupont, Devin E. Montague, Nooria Razai, and Sally M. Yacout
  • “Probing Diels-Alder adducts of anthracene and maleimide as mechanically active functional groups,” Meredith G. Hyatt, Zachary S. Kean, Bobin Lee, and Professor Stephen L. Craig
  • “Metal coordination polymer networks of iron(II) and ruthenium(II) tris(bipyridine),” Kristina M. Vaillonis, Mallory, M. McVannel, Meredith G. Hyatt, Marian L. Pippin, and Dr. Al D. Schwab
  • “Spatial variation of organic volatile compounds associated with gas production operations in southwestern Pennsylvania,” Brittney L. Mitchell, Brandon Miller, Robert Swarthout, Dr. Yong Zhou, and Dr. Barkley C Sive
  • “Hydrocarbon emissions associated with hydraulic fracturing in northeastern Colorado and southwestern Pennsylvania:  A lot of fracking gas,”  Barkley C. Sive, Robert Swarthout, Brandon Miller, Brittney Mitchell, Emily Horsman, Rachel Russo, and Yong Zhou
  • Razvi, S, Folk, D, & Franz, K. (2011, September). Hydrophobic and Hydrophilic Copper Chelators: Pro-oxidants or Anti-oxidants? Poster session presented at the 125th North Carolina American Chemical Society Sectional Meeting, Raleigh, NC.
  • “Metal coordination polymer networks: A modular approach,” Meredith G. Hyatt, Miriam L. Pippin, and Alexander D. Schwab; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
  • “Examination of the beta-amyloid peptide and its copper complexes using spectroscopic methods,”  Michelle D. Maiden and Kassy A. Mies; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
  • “Examination of the binding of iron(III) to the amyloid-beta peptide and its potential implications in Alzheimer’s disease,” Sarah S. Murray and Kassy Mies; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
  •  “Investigation of the interaction between zinc and the beta amyloid peptide,” Rodda A. Ouma and Kassy Mies; 243rd National Meeting of the ACS, San Diego, CA, March 2012.
  •  “Hydrophilic and hydrophobic copper chelators: Pro-oxidants or anti-oxidants?” Sayyeda Zeenat A. Razvi, Drew S. Folk and Katherine J. Franz; 243rd National Meeting of the ACS, San Diego, CA, March 2012.

 

Research Presentations at Meredith College

  • Destiny McDuffie – “Autoinhibitory Regulation in Guanine Nucleotide Exchange Factor H1 (GEF-H1)”
  • Tia Joyce – “The Effects of Asparagusic Acid on Glutamate Dehydrogenase”
  • Crystal Gunther – “Synthesis and analysis of a carbozole-based dye and its use in a Dye-Sensitized Solar Cell”
  • Kimberly Hinton – “Connecting Organic Chemistry and Biochemistry through Synthesized Inhibitors and Succinate Dehydrogenase”
  • Julia Bair – “Investigation of the roles of Several Iron (II) Chelators in the Release of Iron from Ferrioxamine B via Reduction by NADH.”
  • Sarah Beno and Rachel Serrano – “DNA extraction and PCR of Tylosema esculentum and DNA extraction, PCR, and Gene Amplification of nifH in Rhizobium leguminosarum.”
  • Callie Davis – “A Novel Chelation Method from Removing Toxic heavy metals from water Supplies.”
  • Sayyeda Zeenat Razvi – “An Exploration of the Iron Release Mechanism of the Naturally occurring Siderophore, Ferrioxamine B.”
  • Sarah White – “Investigating Porphyrins and Phthalocyanine as Iron (II) Chelators that Facilitate Iron Release from a Siderophore through Reduction by NADH.”
  • Sally Yacout, Nooria Razai, Devin Montague, and Elizabeth Jaimes – “An Efficient Synthetic Route to Isoptilocaulin: Making the Aminocycopentene.”
  • Michelle Maiden – “A Possible Link Between Alzheimer’s Disease and Copper”
  • Sarah Murray – “A study of interactions between Iron and the Amyloid-beta peptide: Potential implications in Alzheimer’s Disease”
  • Meredith Hyatt – “Metal Coordination Polymer Networks:  A Modular Approach”
  • Sayyeda Zeenat Razvi and Kassy Mies – “Iron Release Mechanisms and potential medicinal Applications of naturally Occurring Siderophores”

 

Celebrating Student Achievement Day: Poster Presentations

  • Amanda Krzywinski – “Converting Green Fluorescent Protein into Alternate Colors Using Site-Directed Mutagenesis.”
  • Amanda Krzywinski – “Converting Green Fluorescent Protein into Alternate Colors Using Site-Directed Mutagenesis.”
  • Devin Montague, Nooria Razai and Elizabeth Jaimes – “Convergent Approach to Synthesis of Isoptilocaulin.”
  • Sarah Beno, Rachel Serrano and Anum Imran – DNA Extraction and Regeneration of Tylosema esculentum and Tylosema fassoglensis
  • Emma Keim, Katy Martin and Sally Yacout – Asteroid Search
  • Rodda Ouma – An investigation of the interaction between zinc and the beta amyloid peptide:  A possible cause of the senile plaques characteristic of Alzheimer’s disease

STEM at Meredith College

Learn more about the STEM programs at Meredith College.

 

Learn more about the STEM programs at Meredith College.

Contact Information
Sasha Ormond
Chair, Dept. of Chemistry, Physics, & Geoscience
203 Science/Mathematics Bldg.
(919) 760-2399
ormonda@meredith.edu
Chemistry Physics & Geoscience Department »
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